the answer varies from a tome to one line "use whatever you are comfortable with". let me tread the middle path.
what do you mean by an indicator? if it is a tool that indicates something, then even P and V can be considered to be an indicator and so thats the end of the matter. whatever indicates what you require, use it.
if u believe that indicators are the tools that are DERIVED from P, V, T etc, then you can view it like this: indicators help you in seeing the snapshot. How?
It may be cutting through the noise;
or combining several elements that you cannot ordinarily "derive" by just looking at price volume etc. ;
comparing several elements OTHER than price and volume;
cutting out subjectivity from your PV interpretation etc.
So what snapshot do you want? This will very well answer your indicator requirement.
1. Overall market direction over the different time frames.
2. Quality of the market move.
3. What the big money is doing?
4. What is the speed of the move?
5. What is the market sentiment?
6. What is the strength of the market move?
7. What is the volatility persisting over the current period?
These are some of the questions that will need mathematical manipulation of price, volume, time and other factors over a certain period of time, which essentially we call as INDICATORS.
In case you dont need these and just want to see if in the last 1 hour what P,V is doing to take a position for the next 3 minutes, go ahead. thats your NEED. Nothing else is required for you.
Hope that answers to some extent.
To end, theres no answer as to whether it is lunar cycle or bicycle that works. neither is it the issue of whether it is a non stationary time series or just random numbers. it again depends on the way you look at the market and utilize your theory to interpret it.
whereas Ehler's Dominant Cycle Analysis depends on the presence of real cycles, Juriks JMA is a causal nonlinear adaptive filter that cleans non stationary time series data, while william blau balances smoothness and lag in momentum oscillators by using double smoothing.